Critical Assessment of protein Structure Prediction
Biennial competition that benchmarks computational protein structure prediction; AlphaFold 2's dominant performance at CASP14 marked a turning point in the field.
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DeepMind's AlphaFold 2 Achieves Highest-Accuracy Results at CASP14 Protein Structure Prediction Competition
In November–December 2020, DeepMind's AlphaFold 2 system achieved a median Global Distance Test score of approximately 92.4 across all CASP14 targets, far surpassing the next-best group, in a result that computational biologists described as largely solving the 50-year-old protein-folding problem for single-chain proteins.