Drug discovery
AI milestones in drug discovery, part of medicine and health.
2 milestones
MIT Researchers Use Machine Learning to Identify Halicin, an Antibiotic Effective Against Drug-Resistant Bacteria
On 20 February 2020, James Collins and colleagues at MIT published research in Cell describing a deep-learning model trained to predict antibiotic activity; the model identified halicin, a compound previously investigated for diabetes treatment, as a potent broad-spectrum antibiotic capable of killing several drug-resistant bacterial strains.
Nanorobotic drug delivery using flagellated bacteria by team from Polytechnique Montréal
In August 2016, a team led by Sylvain Martel at Polytechnique Montréal published research in Nature Nanotechnology demonstrating that swarms of approximately 100 million flagellated bacteria, each carrying a magnetosome acting as a compass, could transport and release an anticancer drug payload preferentially within the hypoxic regions of a tumour in a mouse model.